Fatty acid amides present in Camembert cheese improved cognitive decline after oral administration in mice
Abstract
Herein, we investigated the effects of Camembert cheese (CC) and its fatty acid contents on cognitive function in mice by employing the object recognition test to evaluate hippocampus-dependent memory. Orally administered CC improved the cognitive decline induced by a high-fat diet. Next, we focused on myristamide (MA), oleamide, and stearamide, which are fatty acid amides produced during the fermentation process of CC. We found that oral administration of MA improved cognitive decline. Notably, an improvement was not observed using myristic acid, a free fatty acid that is not amidated. Thus, fatty acid amidation may contribute to the physiological activity. Moreover, we investigated changes in gene expression related to neurogenesis in the hippocampus. After MA administration, mRNA expression analysis indicated that MA increased hippocampal brain-derived neurotrophic factor expression.
The Attini ants harbor actinobacteria in both the fungal gardens they cultivate and in biofilms on their exoskeletons. These actinobacteria provide the first line of defense against Escovopsis and other pathogens, including Fusarium and Syncephalastrum, known fungal pathogens. The molecules produced by the bacteria have been shown to combat pathogens known for multi-drug resistance, such as Enterococcus, Staphylococcus aureus, Klebsiella, Acinobacter baumannii, Pseudomonas aeruginosa, and Enterobacter. Some molecules have even shown promise in inducing the death of cancer cells in the laboratory.
No, but I am susceptible to infection by S. Aureus, Klebsiella, P. Aeruginosa and the others, and have seen all of these kill people in ICU because suitable antibiotics had not yet been found, so I'll consider this to be good news.
WARNING: The above post may contain thoughts or ideas known to the State of Caliphornia to cause seething rage, confusion, distemper, nausea, perspiration, sphincter release, or cranial implosion to persons who implicitly trust only one news source, or find themselves at either the left or right political extreme. Proceed at your own risk.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
WARNING: The above post may contain thoughts or ideas known to the State of Caliphornia to cause seething rage, confusion, distemper, nausea, perspiration, sphincter release, or cranial implosion to persons who implicitly trust only one news source, or find themselves at either the left or right political extreme. Proceed at your own risk.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
@Amos_Umwhat said:
No, but I am susceptible to infection by S. Aureus, Klebsiella, P. Aeruginosa and the others, and have seen all of these kill people in ICU because suitable antibiotics had not yet been found, so I'll consider this to be good news.
Steve, my comment was satire. I was just "horsing" around.
@Amos_Umwhat said:
No, but I am susceptible to infection by S. Aureus, Klebsiella, P. Aeruginosa and the others, and have seen all of these kill people in ICU because suitable antibiotics had not yet been found, so I'll consider this to be good news.
Steve, my comment was satire. I was just "horsing" around.
Good to know, I wondered. I thought “hmm, he’s usually smarter than that “. But, there are people who think that way.
WARNING: The above post may contain thoughts or ideas known to the State of Caliphornia to cause seething rage, confusion, distemper, nausea, perspiration, sphincter release, or cranial implosion to persons who implicitly trust only one news source, or find themselves at either the left or right political extreme. Proceed at your own risk.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
Anti-Cancer Effects: Short-chain fatty acids from fiber digestion directly modulate genes that regulate cell growth, differentiation, and apoptosis.
Global Mechanism: These fatty acids circulate throughout the body, suggesting fiber’s widespread influence on gene function.
Diet Deficiency: Less than 10% of Americans consume the recommended daily fiber intake, limiting these protective benefits.
Sometimes I wonder what the world would be like if we put the same effort into public transportation as we do into mass destruction of the species.
WARNING: The above post may contain thoughts or ideas known to the State of Caliphornia to cause seething rage, confusion, distemper, nausea, perspiration, sphincter release, or cranial implosion to persons who implicitly trust only one news source, or find themselves at either the left or right political extreme. Proceed at your own risk.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
Star-forming Galaxies Like Grains of Sand
Thousands of galaxies crowd into this Herschel image of the distant Universe. Each dot is an entire galaxy containing billions of stars.
Comments
We actually have nine different species of mints that grow natively here
10.... Fort Knox is a US Mint 😉😙
Depository. They don’t mint anything 😉😘
Just going by the Googs Machine...
Don't go all semantics on me.... it's a mint location.... so there's a shiiit ton of peppermint there.
AI 😒
First word…. Artificial
No the first word is AL. Don't know who this Al guy is, but I know he's really smart.
Fatty acid amides present in Camembert cheese improved cognitive decline after oral administration in mice
Abstract
Herein, we investigated the effects of Camembert cheese (CC) and its fatty acid contents on cognitive function in mice by employing the object recognition test to evaluate hippocampus-dependent memory. Orally administered CC improved the cognitive decline induced by a high-fat diet. Next, we focused on myristamide (MA), oleamide, and stearamide, which are fatty acid amides produced during the fermentation process of CC. We found that oral administration of MA improved cognitive decline. Notably, an improvement was not observed using myristic acid, a free fatty acid that is not amidated. Thus, fatty acid amidation may contribute to the physiological activity. Moreover, we investigated changes in gene expression related to neurogenesis in the hippocampus. After MA administration, mRNA expression analysis indicated that MA increased hippocampal brain-derived neurotrophic factor expression.
https://www.sciencedirect.com/science/article/pii/S0168010224000403
We are going to have some of the longest lived, healthiest mice in the world.
Trapped in the People's Communist Republic of Massachusetts.
Looking at buried parts of identity.
Jung believed we all have a Shadow self. Facing up to it could help you live more fully and be more forgiving of others
https://psyche.co/ideas/three-ways-to-get-in-touch-with-your-shadow-self
The Attini ants harbor actinobacteria in both the fungal gardens they cultivate and in biofilms on their exoskeletons. These actinobacteria provide the first line of defense against Escovopsis and other pathogens, including Fusarium and Syncephalastrum, known fungal pathogens. The molecules produced by the bacteria have been shown to combat pathogens known for multi-drug resistance, such as Enterococcus, Staphylococcus aureus, Klebsiella, Acinobacter baumannii, Pseudomonas aeruginosa, and Enterobacter. Some molecules have even shown promise in inducing the death of cancer cells in the laboratory.
https://entomologytoday.org/2025/01/07/fungus-farming-ants-attini-new-antimicrobial-compounds/
You're not an ant. Seriously y'all, just stop it.
No, but I am susceptible to infection by S. Aureus, Klebsiella, P. Aeruginosa and the others, and have seen all of these kill people in ICU because suitable antibiotics had not yet been found, so I'll consider this to be good news.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
Steve, my comment was satire. I was just "horsing" around.
Good to know, I wondered. I thought “hmm, he’s usually smarter than that “. But, there are people who think that way.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
@Amos_Umwhat I’m reading this book too.
A good cigar and whiskey solve most problems.
"One Deadly Eye" by Randy Wayne White. A Doc Ford novel about a hurricane's eye.
10 largest passenger planes…
https://www.aerotime.aero/articles/top-10-largest-passenger-planes-in-the-world?utm_source=ActiveCampaign&utm_medium=email&utm_content="We are at cruising altitude " Turkka Kuusisto, CEO Finnair ✈&utm_campaign=AeroTime News / January 11, 2025&vgo_ee=57ygrLRjSBhqkf0f04JLrqr2MP0OyJJDALT7TPCopCxPAGyq:bN3tQAlSfSiYiMmU5ZxuWGixfOgcBpNi
A good cigar and whiskey solve most problems.
Worst in Show 2025: Not All Innovation Is Good Innovation
The Most Overengineered, Unrepairable, and Unsustainable Tech Disasters at CES
https://www.ifixit.com/News/107510/worst-in-show-2025-not-all-innovation-is-good-innovation
How Fiber Fuels Anti-Cancer Gene Activity
Key Facts
Anti-Cancer Effects: Short-chain fatty acids from fiber digestion directly modulate genes that regulate cell growth, differentiation, and apoptosis.
Global Mechanism: These fatty acids circulate throughout the body, suggesting fiber’s widespread influence on gene function.
Diet Deficiency: Less than 10% of Americans consume the recommended daily fiber intake, limiting these protective benefits.
https://neurosciencenews.com/epigenetics-fiber-cancer-28349/
https://www.twz.com/news-features/what-the-navys-massive-orca-submarine-drone-is-actually-capable-of
Sometimes I wonder what the world would be like if we put the same effort into public transportation as we do into mass destruction of the species.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain
Star-forming Galaxies Like Grains of Sand
Thousands of galaxies crowd into this Herschel image of the distant Universe. Each dot is an entire galaxy containing billions of stars.
https://www.herschel.caltech.edu/image/nhsc2010-008a
Looks like some deep-pile carpeting from the 70's.
How Neandertal DNA May Affect the Way We Think
https://www.scientificamerican.com/article/how-neandertal-dna-may-affect-the-way-we-think/
"The Concrete Blonde" by Michael Connelly. Good read.
"The Poet" by Michael Connelly" One of his best works.