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I could see you in one of those, Edward. And just think of all the people downstream you'd be helping - the employees, their families, the vendors making parts - that would feel nice, wouldn't it?
"I could've had a Mi Querida!" Nick Bardis2 -
And I'd save time. My station wagon takes 5.6 seconds to get up to 60 mph.
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Cancer cells may be tapping into an unexpected energy source: an antioxidant long associated with protecting healthy cells. Researchers have discovered that tumors appear to be “addicted” to glutathione, a molecule widely known for preventing cellular damage, which they use as a key fuel source. The discovery not only challenges conventional thinking about antioxidants but also highlights a possible new target for cancer treatment.
https://scitechdaily.com/scientists-discover-cancer-tumors-are-addicted-to-this-common-antioxidant/
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Easy Wall Hangings, Plant Hangers, and Jewelry by Mack Ramay
"I could've had a Mi Querida!" Nick Bardis0 -
They conclude that TREM-1-directed therapies hold translational potential, particularly for patients with sepsis, rheumatoid arthritis, gout, and Alzheimer’s disease, and call for well-designed clinical trials to define therapeutic windows and identify responsive patient subgroups.
Key Questions Answered:
Q: If TREM-1 is an “amplifier,” why does the body have it in the first place?
A: It’s an evolutionary survival tool. When you have a massive infection, you want your immune system to hit back hard and fast. TREM-1 provides that “boost.” The problem arises in modern chronic diseases where the amplifier stays cranked to 11 long after the “intruder” is gone, causing the body to attack its own tissues.Q: Could a TREM-1 drug treat both a swollen knee and memory loss?
A: Potentially! Because TREM-1 is a fundamental part of the myeloid immune response (found in both the joints and the brain’s microglia), a drug that blocks it could theoretically dampen inflammation across different organs. It’s a “one-stop-shop” approach to precision medicine.Q: How close are we to actually getting these treatments?
A: We are in the “translational” phase. While results in the lab (preclinical) are very strong, the “nanobiotide” mentioned is currently in clinical stages. The next big hurdle is human trials to ensure the drugs don’t accidentally shut down the entire immune system while trying to fix the inflammation.https://neurosciencenews.com/trem-1-inflammation-arthritis-alzheimers-30474/
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Completely shutting down the immune system would be a little bit on the downside.
Trapped in the People's Communist Republic of Massachusetts.
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The man who watches Trump all day, every day
Aaron Rupar spends up to 80 hours a week following the US president, from meandering speeches to impromptu press conferences. He says it’s ‘pretty bleak’https://www.thetimes.com/us/american-politics/article/aaron-rupar-bluesky-twitter-trump-z02t3dxng
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That sounds a little creepy. Just off the top of my head, no time to read the whole thing right now, but if I remember, which is always questionable.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain0 -
my wife was into macrame back in her hippy daze if that counts.
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ah, psychology...
Replication crisis plagues studies
A yearslong project reviewing the results of social science studies found that barely half stood up to scrutiny. Since 2011, the “replication crisis” has devastated much of science, notably psychology; hundreds of high-profile findings turned out to be the result of poor statistical practice and bad incentives. Doubt has been cast over the reality of famous discoveries such as the Dunning-Kruger effect, growth mindset, and power posing. The latest research found that many papers failed to give enough information about their methods to replicate them, and that of those that did, 49% failed to reach the statistical threshold for discovery. An earlier project found barely a third of results could be repeated: Perhaps ironically, that finding apparently does replicate.0 -
sound familiar, humans?
These Chimps Began the Bloodiest ‘War’ on Record. No One Knows Why.
A long-running conflict in a Ugandan park may provide clues to the origins of human warfare, and how to avoid it.3 -
@silvermouse said:
sound familiar, humans?These Chimps Began the Bloodiest ‘War’ on Record. No One Knows Why.
A long-running conflict in a Ugandan park may provide clues to the origins of human warfare, and how to avoid it.Funny, I was watching "Chimp Empire", this very same group of chimps, on Netflix last night and thinking to myself that we may not have really evolved all that much. So much of their activity revolves around status, position in the community, and not getting along with the other chimp groups, that are exactly like whichever group.
The more it changes, the more it stays the same.
"If you do not read the newspapers you're uninformed. If you do read the newspapers, you're misinformed." -- Mark Twain2 -
"Broken Prey" by John Sandford. 2005. I just like sitting down, grabbing a book, a cup of Peter's finest, a cigar and a hour or so of relaxation. No electronics.
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dear God, please save us from this golden calf
Trump administration unveils 250-foot 'Triumphal Arch' design
8 hours ago2 -
Weekly ER visits for tick bites reach highest level in nearly a decade. Will this season be worse?
https://abcnews.com/Health/weekly-er-visits-tick-bites-reach-highest-level/story
I Found a female black legged tick on my back, sent it off for testing, came back positive for Lyme, not unusual on the Cape. Rachel found a couple on her before they dug in. Having had a couple of tick-borne disease that took a few years to completely recover from, I take no chances.
Test Results
Pathogen
Borrelia general species
PositiveBorrelia burgdorferi sensu lato
Positive6 -
Many people are concerned but more don't care since it is unlikely to be "catastrophic" before they die.
A vital system of Atlantic Ocean currents is weakening and closer to collapse than thought, new studies find
https://www.cnn.com/2026/04/16/climate/atlantic-ocean-circulation-collapse-update
In an hourlong address before the U.N. General Assembly on Sept. 23, President Donald Trump lashed out at those promoting “the green energy agenda,” saying it had left many European countries “on the brink of destruction” and dismissing climate change as a “hoax” and “the greatest con job ever perpetrated on the world.”
Along the way, Trump made numerous false and misleading claims about renewable energy and climate change, many of which we’ve fact-checked before.
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Three Years or Thirty-six Thousand Miles
By Warren Tee
"I could've had a Mi Querida!" Nick Bardis2 -
White House press secretary Karoline Leavitt said Friday that the Trump administration is looking into whether there may be a link among nearly a dozen American scientists who have reportedly died or gone missing in the past almost three years.
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"I've argued that, soon after the evolution of language, humans recreated their species from the top down. The soul meme proved to be extraordinarily potent – psychologically, ethically, politically. And from the moment it took off among our ancestors, it must have been highly adaptive, transforming human relationships, encouraging new levels of mutual respect, and greatly increasing the value each person puts on their own and others’ lives."
https://aeon.co/essays/you-know-what-consciousness-is-you-live-in-soul-land
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@silvermouse said:
Weekly ER visits for tick bites reach highest level in nearly a decade. Will this season be worse?https://abcnews.com/Health/weekly-er-visits-tick-bites-reach-highest-level/story
I Found a female black legged tick on my back, sent it off for testing, came back positive for Lyme, not unusual on the Cape. Rachel found a couple on her before they dug in. Having had a couple of tick-borne disease that took a few years to completely recover from, I take no chances.
Test Results
Pathogen
Borrelia general species
PositiveBorrelia burgdorferi sensu lato
PositiveYes.look at the experiments on ticks in Pa, purely conspiracy theory as of yet. Very cool winter and several cases of ticks , first in Feb. Ticks new to the area, and reports of research done around Presque Isle Pa. Situations getting drastically worse.
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Just finished "Broken Prey" by John Sandford written in 2005. One of the threads woven into the book is the main character trying to put together a list of the one hundred best rock and roll songs. The thread comes and goes and lists one song here and there. The last two pages of the book
lists all the songs. What a treat.4 -
Man Charged in Lego Theft Scheme of Replacing Pieces With Pasta, Police Say
A California man was charged with grand theft after the police said he reaped about $34,000 in what an official called an “off the charts” pasta-and-switch scheme involving Lego kits.4 -
Lego my eggo.
Trapped in the People's Communist Republic of Massachusetts.
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@edz said:
@silvermouse said:
Weekly ER visits for tick bites reach highest level in nearly a decade. Will this season be worse?https://abcnews.com/Health/weekly-er-visits-tick-bites-reach-highest-level/story
I Found a female black legged tick on my back, sent it off for testing, came back positive for Lyme, not unusual on the Cape. Rachel found a couple on her before they dug in. Having had a couple of tick-borne disease that took a few years to completely recover from, I take no chances.
Test Results
Pathogen
Borrelia general species
PositiveBorrelia burgdorferi sensu lato
PositiveYes.look at the experiments on ticks in Pa, purely conspiracy theory as of yet. Very cool winter and several cases of ticks , first in Feb. Ticks new to the area, and reports of research done around Presque Isle Pa. Situations getting drastically worse.
I'd check the suspect lab for any Wuhan connections.
Don't let the wife know what you spend on guns, ammo or cigars.
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Iceland Just Got Its First Mosquitoes
Join us on Zoom vHerf (Meeting # 2619860114 Password vHerf2020 )1 -
