@ShawnOL said:
I used to buy albums as they came out
and had a decent collection of cassettes. Fast forward many years and im rebuilding my collection with cds. Next two bands to buy up: kiss and Metallica. What should I buy next?
Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
Highlights
Aging induces cytoplasmic localization of angiogenin to produce Glu-5′tsRNA-CTC
Glu-5′tsRNA-CTC disrupts mitochondrial translation and cristae organization
Cristae ultrastructure is required to maintain glutamate homeostasis in the brain
ASO targeting Glu-5′tsRNA-CTC rescues memory decline in aged mice
Struggling with this now, so I find it informative, got to be my own advocate.
European Society of Endocrinology and Endocrine Society Joint Clinical Guideline: Diagnosis and Therapy of Glucocorticoid-induced Adrenal Insufficiency
"A recent study reports something strange: When mice with Alzheimer's disease inhale menthol, their cognitive abilities improve. It seems the chemical compound can stop some of the damage done to the brain that's usually associated with the disease."
@silvermouse said:
"A recent study reports something strange: When mice with Alzheimer's disease inhale menthol, their cognitive abilities improve. It seems the chemical compound can stop some of the damage done to the brain that's usually associated with the disease."
Organisms in sauerkraut protect gut against antibiotics
The minuscule viruses that infect beneficial bacteria living in sauerkraut can be used to help maintain a healthy gut during treatment with antibiotics, a new study in mice suggests.
Yogurt is often thought of as a good source of healthy bacteria for the gut. All bacteria, including those in our intestines and in the food we eat, are infected by such viruses, known as phages.
Sauerkraut contains even more bacteria than yogurt, as long as it has not been pasteurized or treated with preservatives, the researchers said in a presentation at the Digestive Disease Week meeting in Washington.
To make the sauerkraut, researchers fermented cabbage in a salt solution, then removed the bacteria from the sauerkraut juice and purified the phages.
Next, the researchers gave antibiotics to mice, to disrupt the balance of their healthy gut bacteria. Antibiotics typically kill off healthy bacteria and leave room for disease-causing bacteria to take their place, explained study leader Cristina Coffman of The Biomedical Research Institute of New Mexico in Albuquerque.
A few days later, some of the mice were fed the bacteria-infecting viruses from the sauerkraut juice, in their drinking water. Two weeks later, proportions of healthy gut bacteria were found to be depleted in the untreated mice, but the sauerkraut phages had prevented this disruption in the treated mice, the researchers found.
“In addition to this effect on the microbiome, sauerkraut (phages) also had an interesting biologic impact” the researchers said. Weight gain associated antibiotic treatment appeared to be blocked by sauerkraut phages, they said.
The researchers tested a mixed population of phages against the effects of five different antibiotics, Coffman said.
“We are hoping to learn more about how the phages shape the bacteria populations in the intestines and to find therapeutic uses for the phages,” Coffman said.
"In a decade’s time, we may look back at 2024 as the golden age of the web, when most of it was quality human-generated content, before the bots took over and filled the web with synthetic and increasingly low-quality AI-generated content."
Ticketmaster hacked. Breach affects more than half a billion users.
Emails, phone numbers, addresses, and even financial details have allegedly been exposed by a notorious hacker group.
"Shifting gears to another key point in the book: democracy, which you describe as the one form of government that allows the possibility of change without violence. But you also admit, and this is a quote: “Our governance systems—long ago co-opted as instruments for amplified personal power— have become nearly useless, at all levels, from the United Nations to the local city council. Institutions established during 450 generations of unresolvable conflict cannot facilitate change because they are designed to be agents of social control, maintaining what philosopher John Rawls called ‘the goal of the well-ordered society.’ They were not founded with global climate change, the economics of well-being, or conflict resolution in mind.”
So what you are essentially saying here is that anyone trying to adopt the Darwinian principles that you and Sal are advocating is going to be going up against established societal structures, which makes you, by definition, an enemy of the state.
Comments
13 shots will do that to you...
https://neurosciencenews.com/glutamate-trna-alzheimers-26098/
Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
Highlights
Aging induces cytoplasmic localization of angiogenin to produce Glu-5′tsRNA-CTC
Glu-5′tsRNA-CTC disrupts mitochondrial translation and cristae organization
Cristae ultrastructure is required to maintain glutamate homeostasis in the brain
ASO targeting Glu-5′tsRNA-CTC rescues memory decline in aged mice
Struggling with this now, so I find it informative, got to be my own advocate.
European Society of Endocrinology and Endocrine Society Joint Clinical Guideline: Diagnosis and Therapy of Glucocorticoid-induced Adrenal Insufficiency
https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgae250/7667842
"A recent study reports something strange: When mice with Alzheimer's disease inhale menthol, their cognitive abilities improve. It seems the chemical compound can stop some of the damage done to the brain that's usually associated with the disease."
https://www.sciencealert.com/unexpected-connection-between-menthol-and-alzheimers-discovered-in-mice
Who the hell came up with the idea of giving mice with alzheimers a pack of menthols?
Trapped in the People's Communits Republic of Massachusetts.
That's Kool. ;-)
Hmm, might need to rub some Vicks VapoRub™ on my upper lip.
Organisms in sauerkraut protect gut against antibiotics
The minuscule viruses that infect beneficial bacteria living in sauerkraut can be used to help maintain a healthy gut during treatment with antibiotics, a new study in mice suggests.
Yogurt is often thought of as a good source of healthy bacteria for the gut. All bacteria, including those in our intestines and in the food we eat, are infected by such viruses, known as phages.
Sauerkraut contains even more bacteria than yogurt, as long as it has not been pasteurized or treated with preservatives, the researchers said in a presentation at the Digestive Disease Week meeting in Washington.
To make the sauerkraut, researchers fermented cabbage in a salt solution, then removed the bacteria from the sauerkraut juice and purified the phages.
Next, the researchers gave antibiotics to mice, to disrupt the balance of their healthy gut bacteria. Antibiotics typically kill off healthy bacteria and leave room for disease-causing bacteria to take their place, explained study leader Cristina Coffman of The Biomedical Research Institute of New Mexico in Albuquerque.
A few days later, some of the mice were fed the bacteria-infecting viruses from the sauerkraut juice, in their drinking water. Two weeks later, proportions of healthy gut bacteria were found to be depleted in the untreated mice, but the sauerkraut phages had prevented this disruption in the treated mice, the researchers found.
“In addition to this effect on the microbiome, sauerkraut (phages) also had an interesting biologic impact” the researchers said. Weight gain associated antibiotic treatment appeared to be blocked by sauerkraut phages, they said.
The researchers tested a mixed population of phages against the effects of five different antibiotics, Coffman said.
“We are hoping to learn more about how the phages shape the bacteria populations in the intestines and to find therapeutic uses for the phages,” Coffman said.
" Judgment Pray" By John Sanford. A Lucas Davenport and that F u king Flowers novel 2023. Davenport is now driving a Porsche Cayenne hybrid.
Interesting agglomerative news source
https://www.semafor.com/
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) in 2023
https://www.sciencedirect.com/science/article/pii/S1568997223000216?via=ihub
"In a decade’s time, we may look back at 2024 as the golden age of the web, when most of it was quality human-generated content, before the bots took over and filled the web with synthetic and increasingly low-quality AI-generated content."
https://theconversation.com/eat-a-rock-a-day-put-glue-on-your-pizza-how-googles-ai-is-losing-touch-with-reality-230953
Another massive breach...
Ticketmaster hacked. Breach affects more than half a billion users.
Emails, phone numbers, addresses, and even financial details have allegedly been exposed by a notorious hacker group.
https://mashable.com/article/ticketmaster-data-breach-shinyhunters-hack
I take The Epoch Times articles with a grain of salt but this is interesting speculation
Is Gain-of-Function Responsible for the Bird Flu Jump to Cows and Humans?: https://www.theepochtimes.com/health/bird-flu-jumps-twice-to-humans-how-concerned-we-should-be-5648232?
The Collapse Is Coming. Will Humanity Adapt?
An evolutionary biologist and a science fiction writer walk into a bar … and mull over survival.
https://nautil.us/the-collapse-is-coming-will-humanity-adapt-626051/
"Shifting gears to another key point in the book: democracy, which you describe as the one form of government that allows the possibility of change without violence. But you also admit, and this is a quote: “Our governance systems—long ago co-opted as instruments for amplified personal power— have become nearly useless, at all levels, from the United Nations to the local city council. Institutions established during 450 generations of unresolvable conflict cannot facilitate change because they are designed to be agents of social control, maintaining what philosopher John Rawls called ‘the goal of the well-ordered society.’ They were not founded with global climate change, the economics of well-being, or conflict resolution in mind.”
So what you are essentially saying here is that anyone trying to adopt the Darwinian principles that you and Sal are advocating is going to be going up against established societal structures, which makes you, by definition, an enemy of the state.
Yes."